161 research outputs found
Efficient Fast-Convolution-Based Waveform Processing for 5G Physical Layer
This paper investigates the application of fast-convolution (FC) filtering
schemes for flexible and effective waveform generation and processing in the
fifth generation (5G) systems. FC-based filtering is presented as a generic
multimode waveform processing engine while, following the progress of 5G new
radio standardization in the Third-Generation Partnership Project, the main
focus is on efficient generation and processing of subband-filtered cyclic
prefix orthogonal frequency-division multiplexing (CP-OFDM) signals. First, a
matrix model for analyzing FC filter processing responses is presented and used
for designing optimized multiplexing of filtered groups of CP-OFDM physical
resource blocks (PRBs) in a spectrally well-localized manner, i.e., with narrow
guardbands. Subband filtering is able to suppress interference leakage between
adjacent subbands, thus supporting independent waveform parametrization and
different numerologies for different groups of PRBs, as well as asynchronous
multiuser operation in uplink. These are central ingredients in the 5G waveform
developments, particularly at sub-6-GHz bands. The FC filter optimization
criterion is passband error vector magnitude minimization subject to a given
subband band-limitation constraint. Optimized designs with different guardband
widths, PRB group sizes, and essential design parameters are compared in terms
of interference levels and implementation complexity. Finally, extensive coded
5G radio link simulation results are presented to compare the proposed approach
with other subband-filtered CP-OFDM schemes and time-domain windowing methods,
considering cases with different numerologies or asynchronous transmissions in
adjacent subbands. Also the feasibility of using independent transmitter and
receiver processing for CP-OFDM spectrum control is demonstrated
Näin hoidan sarveiskalvovammat
VertaisarvioituSarveiskalvovammoihin liittyy aina näöntarkkuuden pysyvän heikentymisen riski. Suuri osa vammoista paranee kuitenkin ilman merkittäviä jälkiseurauksia. Yleislääkäri voi hoitaa monet pienehköt vammat. Silti kaikkien kliinikoiden tulisi tunnistaa tilanteet, joissa silmälääkärin konsultaatio on välttämätön. Hoidon tavoitteet ovat aina kivun lievitys, silmän rakenteiden suojaaminen, sarveiskalvon arpeutumisen, tulehtumisen ja verisuonittumisen estäminen sekä näöntarkkuuden säilyttäminen.Peer reviewe
Modelling the effect of habitat composition and roads on the occurrence and number of moose damage at multiple scales
We modelled the effect of habitat composition and roads on the number and occurrence of moose (Alces alces L.) damage in Ostrobothnia and Lapland using a zero-inflated count model. Models were developed for 1 km2, 25 km2 and 100 km2 landscapes consisting of equilateral rectangular grid cells. Count models predict the number of damage, i.e. the number of plantations and zero models the probability of a landscape being without damage for a given habitat composition. The number of moose damage in neighboring grid cells was a significant predictor in all models. The proportion of mature forest was the most frequent significant variable, and an increasing admix-ture of mature forests among plantations increased the number and occurrence of damage. The amount of all types of plantations was the second most common significant variable predicting increasing damage along with increasing amount of plantations. An increase in thinning forests as an admixture also increased damage in 1 km2 landscapes in both areas, whereas an increase in pine-dominated thinning forests in Lapland reduced the number of damage in 25 km2 landscapes. An increasing amount of inhabited areas in Ostrobothnia and the length of connecting roads in Lapland reduced the number of damage in 1 and 25 km2 landscapes. Differences in model vari-ables between areas suggest that models of moose damage risk should be adjusted according to characteristics that are specific to the study area.We modelled the effect of habitat composition and roads on the number and occurrence of moose (Alces alces L.) damage in Ostrobothnia and Lapland using a zero-inflated count model. Models were developed for 1 km(2), 25 km(2) and 100 km(2) landscapes consisting of equilateral rectangular grid cells. Count models predict the number of damage, i.e. the number of plantations and zero models the probability of a landscape being without damage for a given habitat composition. The number of moose damage in neighboring grid cells was a significant predictor in all models. The proportion of mature forest was the most frequent significant variable, and an increasing admixture of mature forests among plantations increased the number and occurrence of damage. The amount of all types of plantations was the second most common significant variable predicting increasing damage along with increasing amount of plantations. An increase in thinning forests as an admixture also increased damage in 1 km(2) landscapes in both areas, whereas an increase in pine-dominated thinning forests in Lapland reduced the number of damage in 25 km(2) landscapes. An increasing amount of inhabited areas in Ostrobothnia and the length of connecting roads in Lapland reduced the number of damage in 1 and 25 km(2) landscapes. Differences in model variables between areas suggest that models of moose damage risk should be adjusted according to characteristics that are specific to the study area.Peer reviewe
Bioimpedance spinal needle provides high success and low complication rate in lumbar punctures of pediatric patients with acute lymphoblastic leukemia
Publisher Copyright: © 2022, The Author(s).In this prospective single-arm study of 50 pediatric patients with acute lymphoblastic leukemia (ALL), we evaluated the clinical performance of a novel bioimpedance spinal needle system in 152 intrathecal treatment lumbar punctures (LP) of these patients. The system detects in real-time when the needle tip reaches the cerebrospinal fluid (CSF) in the spinal canal. The success was defined as getting a CSF sample and/or administering the intrathecal treatment with one needle insertion. Incidence of traumatic LP (TLP) was defined as ≥ 10 erythrocytes/µL of CSF. Post-procedural complications were monitored with a one-week diary and one-month register follow-up. The success of the first attempt was 79.5%, with the CSF detection sensitivity of 86.1%. The incidence of TLP was 17.3%. A successful first attempt was associated with a significantly lower incidence of TLP (10% vs 40%, p = 0.0015). During the week after the procedure, the incidence of post-dural puncture headache was 6%. During the follow-up, no major complications were observed. In conclusion, the novel bioimpedance spinal needle system achieved a high success rate and low incidence of TLP and other complications in pediatric patients with ALL in a real-world clinical setting, indicating clinical utility for this system in pediatric hemato-oncology.Peer reviewe
The isotropic Compton profile difference across the phase transition of VO
We studied the isotropic Compton profile of the prototypical oxide VO
across the temperature induced electronic and structural phase transition at
T 340 K. We show that the phase transition leaves an observable
signal, which facilitates Compton scattering studies of electronic structure
and phase transitions in complex solids in powder form. We compare the
experimental results with density functional theory calculations and find
agreement in the shape of the difference profile, although the amplitude of the
observed features is overestimated. The origin of the disagreement is discussed
and we argue that it mainly originates mostly correlation effects beyond our
current calculations and possibly to some extent, from thermal motion
Synovial fluid detection in intra-articular injections using a bioimpedance probe (BIP) needle-a clinical study
Intra-articular glucocorticoid injections are the recommended treatment for active arthritis, but accurate positioning of the needle may be challenging. Inexperienced physicians might decide not to inject because an unsuccessful injection impairs clinical outcome and may lead to complications; however, choosing not to inject may impair or delay the best possible treatment. Here, we address this problem by introducing a novel Bioimpedance Probe (BIP) Needle-guidance method that was tested in a clinical study. The BIP Needle was utilized for detection of synovial fluid. It measures real-time bioimpedance spectra and identifies when the needle tip is in contact with the synovial fluid. Injections into 80 joints with active arthritis were performed by an experienced rheumatologist using the BIP Needle. The location of the BIP Needle was ensured by aspiration of synovial fluid, absence of resistance during injection, and/or using real-time ultrasound imaging. Sensitivity and specificity of the device for synovial fluid detection were 86 % (CI 75-93 %) and 85 % (CI 74-92 %), respectively. The BIP Needles showed high spatial resolution and differentiated the synovial fluid from the surrounding tissues. However, lack of synovial fluid, anatomic variability, and intra-articular structures challenged the technology. The BIP Needles provided adequate results in intra-articular injections. Performance of the device was good even in small joints, which may be the most difficult for inexperienced physicians. Further performance improvement can be expected when more data is collected for mathematical models. Overall, this novel method showed potential to be used in real-time needle guidance.Peer reviewe
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